Interactions between entomopathogenic fungi and their hosts

Team of work

Principal InvestigatorHuarte Bonnet

Huarte Bonnet, Carla

Investigator
carlahb@biol.unlp.edu.ar

Mannino, ConstanzaMannino

Investigator
constanza.mannino@gmail.com

Dulbecco, AndreaDulbecco

Research Fellow
adulbecco@med.unlp.edu.ar

Moriconi, DéboraMoriconi

Research Fellow
debomoriconi@hotmail.com

Davyt Colo, BelénDavyt

Research Fellow
bdavyt@gmail.com

Espin, Daysi Espin

Research Fellow
daysi97espinsanchez@gmail.com

Preisegger, LautaroPreisegger

Research Fellow
lautaropreisegger@gmail.com

Collaborators from other institutions

Abreo, Eduardo
Instituto Nacional de Investigación Agropecuaria (INIA). Las Brujas, Canelones, Uruguay.

Fernandes, Éverton K. K.
Instituto de Patología Tropical y Salud Pública (IPTSP), Universidad Federal de Goiás, Brasil.

Fan, Yanhua
Southwest University, Chongqing, China.

Ortíz-Urquiza, Almudena
School of Biosciences, University of Nottingham, UK.

Cardozo, Rubén M.
Instituto de Patología Experimental, Facultad de Ciencias de la Salud, Universidad Nacional de Salta, Salta.

Cingolani, Fernanda
Centro de Estudios Parasitológicos y de Vectores, CONICET-UNLP, La Plata.

Diambra, Luis
Centro Regional de Estudios Genómicos, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata.

Foieri, Alvaro
Unidades de Investigaciones Anexo Museo, Facultad de Ciencias Naturales y Museo, Universidad Nacional de La Plata, La Plata.

Franceschini, Celeste
Centro de Ecología Aplicada del Litoral (Consejo Nacional de Investigaciones Científicas y Técnicas - Universidad Nacional de Nordeste), Corrientes.

Padín, Susana B.
Cátedra de Terapéutica Vegetal, Facultad de Ciencias Agrarias y Forestales, Universidad Nacional de La Plata, La Plata.

Rueda Páramo, Manuel
Centro de Estudios Parasitológicos y de Vectores, CONICET-UNLP, La Plata.

Russo, Leticia
Instituto de Botánica Carlos Spegazzini, FCNyM- UNLP, La Plata.

Scorsetti, Ana Clara
Instituto de Botánica Carlos Spegazzini, FCNyM- UNLP, La Plata.

Toledo, Andrea
Centro de Investigaciones en Fitopatologias (CIC), Facultad de Ciencias Agrarias y Forestales, Universidad Nacional de La Plata, La Plata.

Trejo, Sebastián
YPF - Tecnología (YTEC), Berisso, Buenos Aires, Argentina.

Zilli, Carla
Instituto de Investigaciones en Biociencias Agrícolas y Ambientales (Faculta de Agronomía, UBA).

Line overview

Our interest is focused on the biochemical and molecular interactions between the entomopathogenic fungi (Hypocreales) Beauveria bassiana, Metarhizium anisopliae and M. robertsii and their hosts, including insects (fungi as pathogens) and plants (fungi as endophytes).
Our lines of research include insect host such as kissing bugs, mosquitoes, weevils and phytophagous bugs, as well as plant host such as soybean and rice.
These studies have focused on understanding the metabolic pathway of insect lipid degradation by entomopathogenic fungi, but also include the study of fungal genes inducible by different stressors such as growth in hydrocarbons, insect hemolymph, heat or UV radiation.
In addition, we study the genes involved in the synthesis of fungal secondary metabolites such as toxins and other important molecules in both infective and endophytic cycles, as well as the response of the host's immune system during fungus-insect, fungus-plant, and fungus-plant-insect interactions. We use techniques such as real-time quantitative PCR, RNAseq, protein cloning and purification, gene silencing and expression, electroantennography, and gas chromatography coupled to mass spectrometry.

Non-thermal plasma as emerging technology for Tribolium castaneum pest-management in stored grains and flours.
Zilli, Carla; Pedrini, Nicolás; Prieto, Eduardo; Girotti, Juan Roberto; Vallecorsa, Pablo; Ferreyra, Matías; Chamorro, Juan Camilo; Cejas, Ezequiel; Fina, Brenda; Prevosto, Leandro; Balestrasse, Karina.
2022. Journal of stored products research. : PERGAMON-ELSEVIER SCIENCE LTD, vol. 99, ISSN 0022-474X
DOI: 10.1016/j.jspr.2022.102031

Alkane-priming of Beauveria bassiana spores to improve biocontrol of the redbanded stink bug Piezodorus guildinii and the bronze bug Thaumastocoris peregrinus.
L. Sessa, N. Pedrini, N.A. Altier, E. Abreo.
2022. Journal of Invertebrate Pathology
DOI:org/10.1111/eea.13166

Natural incidence of pathogenic fungi on stink bug pests in Argentinian rice paddies.
D. Fuentes, A.V. Toledo, N. Pedrini, A. Sosa, A, M. Santana, M., P. Gervazoni, P., G. Dellapé, G., C. Franceschini.
2022. Entomologia Experimentalis et Applicata.
DOI:org/10.1111/eea.13166

Cytochrome P450 genes of the CYP4 clan and pyrethroid detoxification and resistance in Chagas disease vectors.
A.B. Dulbecco, G.M. Calderón-Fernández, N. Pedrini.
2022. Frontiers in Tropical Diseases 3:823093
DOI:org/10.3389/fitd.2022.823093

Editorial: Entomopathogenic fungi for the control of arthropod pests.
I.C. Angelo, J.L. Ramirez, P.S. Golo, É.K.K. Fernandes, N. Pedrini, V.R.E.P Bittencourt.
2022. Frontiers in Physiology 13:885131
DOI:org/10.3389/fphys.2022.885131

Secretion and detection of defensive compounds by the red flour beetle Tribolium castaneum interacting with the insect pathogenic fungus Beauveria bassiana.
B. Davyt-Colo, B., J.R. Girotti, A. Gonzalez, N. Pedrini.
2022. Pathogens 11:487
DOI:org/10.3390/pathogens11050487

The entomopathogenic fungus Beauveria bassiana shows its toxic side within insects: secondary metabolites gene expression during pathogenesis.
N. Pedrini.
2022. Journal of Fungi, 8,488
DOI: org/10.3390/jof8050488

Tolerance to abiotic factors of microsclerotia and pellets from Metarhizium robertsii, and molecular and ultrastructural changes during microsclerotial differentiation.
F.R.S. Paixão, C. Huarte-Bonnet, C.D.S. Ribeiro-Silva, G.M. Mascarin, E.K.K. Fernandes, N. Pedrini.
2021. Frontiers in Fungal Biology 2:654737
DOI:org/10.3389/ffunb.2021.654737

Knockdown of CYP4PR1, a cytochrome P450 gene highly expressed in the integument tissue of Triatoma infestans, increases susceptibility to deltamethrin in pyrethroid-resistant insects.
A.B. Dulbecco, D.E. Moriconi, N. Pedrini.
2021. Pesticide Biochemistry and Physiology 173: 104781

Epicuticular hydrocarbons of the redbanded stink bug Piezodorus guildinii (Heteroptera: Pentatomidae): Sexual dimorphism and alterations in insects collected in pesticide-treated soybean crops.
L. Sessa, G.M. Calderón-Fernández, E. Abreo, N.A. Altier, S.J. Mijailovsky, J.R. Girotti, N. Pedrini.
2021. Pest Management Science 77: 4892–4902
DOI:org/10.1002/ps.6528

Metarhizium robertsii and M. acridum conidia produced on riboflavin-supplemented medium have increased UV-A tolerance and upregulated photoprotection and photoreactivation genes.
C. Huarte-Bonnet, R.A. Pereira-Junior, F.R.S. Paixão, G.U.L. Braga, D.W. Roberts, C Luz, N. Pedrini, E.K.K. Fernandes.
2020. BioControl 65: 211-222

Outcome of blue, green, red, and white light on Metarhizium robertsii during mycelial growth on conidial stress tolerance and gene expression.
L.P. Dias, N. Pedrini, G.U.L. Braga, P.C. Ferreira, B. Pupin, C.A. Araújo, L.M.P. Corrochano, D.E.N. Rangel.
2020. Fungal Biology 124: 263-272

Isolation of Beauveria bassiana from the Chagas disease vector Triatoma infestans in the Gran Chaco Region of Argentina: Assessment of gene expression during host–pathogen interaction.
L.V. Baldiviezo, N. Pedrini, M. Santana, M.C. Mannino, L.B. Nieva, A.G. Gentile, R.M. Cardozo.
2020. Journal of Fungi, 6: 219
DOI:org/10.3390/jof6040219

Metodologías para la detección de SARS-CoV-2 y análisis de carga viral mediante RT-PCR cuantitativa.
C. Jaquenod De Giusti, M. Montanaro, M.V. Mencucci, R. Canzoneri, A. Orlowski, M. Santana, E. Pereyra, M. Kraemer, S.M.L. Lavarias, V. Moscoso, N. Costantini, F. Francini, H.A. Garda, N. Pedrini, M.R. González Baro, M. Vila Petroff, A. Aiello, M.C. Abba.
2020. Innovación y Desarrollo Tecnológico y Social (UNLP) 2 (2): 1-14

The entomopathogenic fungus Beauveria bassiana produces microsclerotia-like pellets mediated by oxidative stress and peroxisome biogenesis.
C. Huarte-Bonnet, F.R.S. Paixão, G.M. Mascarin, M. Santana, E.K.K. Fernandes, N. Pedrini.
2019. Environmental Microbiology Reports 11(4): 518-524

The Limpet transcription factors of Triatoma infestans regulate the response to fungal infection and modulate the expression pattern of defensin genes.
M. C. Mannino, F.R.S. Paixão, N. Pedrini.
2019. Insect Biochemistry and Molecular Biology 108: 53–60

Is the insect cuticle the only entry gate for fungal infection? Insights into alternative modes of action of entomopathogenic fungi.
M.C Mannino, C. Huarte-Bonnet, B. Davyt-Colo, N. Pedrini.
2019. Journal of Fungi 5:33
DOI:10.3390/jof5020033

The Second International Symposium on Fungal Stress: ISFUS.
A. Alder-Rangel, A. Melo Bailao, A.F. da Cunha, C.M.A. Soares, C. Wang, D. Bonatto, E. Dadachova, E. Hakalehto, E.C.A. Eleutherio, E.K.K. Fernandes, G.M. Gadd, G.H. Braus, G.U.L. Braga, G.H. Goldman, I. Malavazi, J.E. Hallsworth, J.Y. Takemoto, K.K. Fuller, L. Selbmann, L.M. Corrochano, M.R. von Zeska Kress, M.C. Bertolini, M. Schmoll, N. Pedrini, O. Loera, R.D. Finlay, R.M. Peralta, D.E.N. Rangel.
2018. Fungal Biology 122: 386-399

De novo assembly and transcriptome characterization of the freshwater prawn Palaemonetes argentinus: implications for a detoxification response.
C.F. García, N. Pedrini, A. Sánchez-Paz, C.S. Reyna-Blanco, S. Lavarias, A. Muhlia-Almazán, A. Fernández-Giménez, A. Laino, E. de-la-Re-Vega, Lukaszewicz, A.A. López-Zavala, L.G. Brieba, M.F. Criscitello, J.S. Carrazco-Miranda, K.D. García-Orozco, A. Ochoa-Leyva, E. Rudiño-Piñera, A. Sánchez-Flores, R.R. Sotelo-Mundo.
2018. Marine Genomics 37: 74-81

Alkane-grown Beauveria bassiana produce mycelial pellets displaying peroxisome proliferation, oxidative stress, and cell surface alterations.
C. Huarte-Bonnet, F.R.S. Paixão, J.C. Ponce, M. Santana, E.D. Prieto, N. Pedrini.
2018. Fungal Biology 122: 457-464

Natural occurrence of the entomopathogenic genus Pandora on spittlebug pests of crops and pastures in Argentina.
A. Foieri, N. Pedrini, A. Toledo.
2018. Journal of Applied Entomology 142:363–370

Molecular interactions between entomopathogenic fungi (Hypocreales) and their insect host: perspectives from stressful cuticle and hemolymph battlefields and the potential of dual RNA sequencing for future studies.
N. Pedrini.
2018. Fungal Biology 122: 538-545

Insecticidal efficacy of Beauveria bassiana, diatomaceous earth and fenitrothion against Rhyzopertha dominica and Tribolium castaneum on stored wheat.
G. Dal Bello, C. Fusé, N. Pedrini, S. Padín.
2018. International Journal of Pest Management 64: 279-286

Insights into hydrocarbon assimilation in eurotialean and hypocrealean fungi: roles for CYP52 and CYP53 clans of cytochrome P450 genes.
C. Huarte-Bonnet, S. Kumar, M.C.N. Saparrat, J.R. Girotti, M. Santana, J.E. Hallsworth, N. Pedrini.
2018. Applied Biochemistry and Biotechnology 184: 1047-1060

Riboflavin induces Metarhizium spp. to produce conidia with elevated tolerance to UV-B, and upregulates photolyases, laccases and polyketide synthases genes.
R.A. Pereira-Junior, C. Huarte-Bonnet, F.R.S. Paixão, D.W. Roberts, C. Luz, N. Pedrini, E.K.K. Fernandes.
2018. Journal of Applied Microbiology 125(1):159-171

Tracing the coevolution between Triatoma infestans and its fungal pathogen Beauveria bassiana.
M.C. Mannino, M.P. Juárez, N. Pedrini.
20185. Infection, Genetics and Evolution 66: 319-324

Synthesis and secretion of volatile short chain fatty acids in Triatoma infestans infected with Beauveria bassiana.
S. Lobo, J.R. Girotti, S.J. Mijailovsky, E.K.K. Fernandes, C. Luz, N. Pedrini.
2018. Medical and Veterinary Entomology 32: 358–364

Integument CYP genes of the largest genome-wide cytochrome P450 expansions in triatomines participate in detoxification in deltamethrin-resistant Triatoma infestans.
A.B. Dulbecco, D.E. Moriconi, G.M. Calderón-Fernández, S. Lynn, A. McCarthy, J.A. Salamanca-Moreno, M.P. Juárez, N. Pedrini.
2018. Scientific Reports 8:10177
DOI:10.1038/s41598-018-28475-x.

Rhodnius prolixus supergene families of enzymes potentially associated with insecticide resistance.
R. Schama, N. Pedrini, M.P Juárez, D.R. Nelson, A.Q. Torres, D. Valle, R.D. Mesquita.
2016. Insect Biochemistry and Molecular Biology 69: 91–104

Oxidative stress in entomopathogenic fungi grown on insect-like hydrocarbons.
C. Huarte Bonnet, M.P. Juárez, N. Pedrini.
2015. Current Genetics 61(3): 289-297

Unveiling chemical defense in the rice stalk stink bug against the entomopathogenic fungus Metarhizium anisopliae.
R.A. Silva, E.D. Quintela, G.M. Mascarin, N. Pedrini, L.M. Lião, P.H Ferri.
2015. Journal of Invertebrate Pathology 127: 93-100

Biological control of the Chagas disease vector Triatoma infestans with the entomopathogenic fungus Beauveria bassiana combined with an aggregation cue: field, laboratory and mathematical modeling assessment.
L. Forlani, N. Pedrini, J. Girotti, S. Mijailovsky, R. Cardozo, A. Gentile, C. Hernández, J. Rabinovich, M.P. Juárez.
2015. PLoS Neglected Tropical Diseases 9(5): e0003778

Assessing gene expression during pathogenesis: use of qRT-PCR to follow toxin production from the entomopathogenic fungus Beauveria bassiana during infection and immune response of the insect host Triatoma infestans.
L.S. Lobo, W.C. Luz, E.K.K. Fernandes, M.P. Juárez, N. Pedrini.
2015. Journal of Invertebrate Pathology 128: 14-21

Tenebrionid secretions and a fungal benzoquinone oxidoreductase form competing components of an arms race between a host and pathogen.
N. Pedrini, A. Ortiz Urquiza, C. Huarte Bonnet, Y. Fan, M.P. Juárez, N.O. Keyhani.
2015. Proceedings of the National Academy of Sciences USA 112 (28): 3651-3660.

Genome of Rhodnius prolixus, an insect vector of Chagas disease, reveals unique adaptations to hematophagy and parasite transmission.
Mesquita, R.D. Vionette-Amaral, R.J. Lowenberger, C.; Rivera-Pomar, R.; Monteiro, F.A; Minx, P.; Spieth, S.; Carvalho, A.B.; Panzera, F.; Lawson, D.; Torres, A.L.Q.; Ribeiro, J. M.C.; Sorgine, M.H.F.; Waterhouse, R., Montague, M.J.; Abad-Franch, F.; Alves-Bezerra, M.; Amaral, L.R.; Araujo, H; Araujo, R.N; Aravind, L.; Atella, G.C.; Azambuja, P; Berni, M; Bittencourt-Cunha, P.; Braz, G.R.C.; Calderón-Fernández, G.M.; Carareto, C.M.A.; Christensen, M.B.; Costa, I.R.; Costa, S.G.; Dansa-Petretski, M.; Daumas-Filho, C.R.O.; De Paula, I.F.; Dias, F.A.; Dimopoulos, G.; Emrich, S.J.; Esponda-Behrens,N.; Fampa, P; Fernández-Medina, R.D.; Fonseca, R.N.; Fontenele, M.; Fronick, C.; Fulton, L.; Gandara, A.C.P.; Garcia, E.S.; Genta, F.A.; Giraldo-Calderón, G.I.; Gomes, B.; Gomes; Gondim, K.C.; Granzoto, A.; Guarneri, A.A.; Guigó, R.; Harry, M.; Hughes, D.S.T.; Jablonka, W.; Jacquin-Joly, E.; Juárez, M.P.; Koerich, L.B.; Latorre-Estivalis, J.M.; Lavore, A.E.; Lawrence, G.G.; Lazoski, C.; Lazzari, C.R.; Lopes, R.R.; Lorenzo, M.G.; Lugon, M.D.; Majerowicz, D.; Marcet, P.L.; Mariotti,M.; Masuda, H.; Megy, K.; Melo, A.C.A.; Missirlis, F; Mota, T.; Noriega, F.G.; Nouzova, M.; Nunes, R.D.; Oliveira, R.L.L.; Oliveira-Silveira, G.; Ons, S.; Pagola, L.; Paiva-Silva, G.O.; Pascual, A.; Pavan, M.; Pedrini, N.; Peixoto, A.A.; Pereira, M.H.; Pike, A.; Polycarpo, C.; Prosdocimi, F.; Ribeiro-Rodrigues, R.; Robertson, H. M.; Salerno, A.P.; Salmon, D.; Santesmasses, D.; Schama, R.L.; Seabra-Junior, E.S.; Silva-Cardoso, L.; Silva-Neto, M.A.C.; Souza-Gomes, M.; Sterkel, M.; Taracena, M.L.; Tojo, M.; Tu, Z.; Tubío, J.M.C.; Ursic-Bedoya, R.; Venancio, T.M.; Walter-Nuno, A. B.; Wilson, D.; Warren, W.; Wilson, R.K.; Huebner, E.; Dotson, E.M.; Oliveira, P.L.
2015. Proceedings of the National Academy of Sciences USA 112 (48): 14936-14941

Toxicological and biochemical response of the entomopathogenic fungus Beauveria bassiana after exposure to deltamethrin.
L. Forlani, M.P. Juárez, S. Lavarías, N. Pedrini.
2014. Pest Management Science 70: 751–756

Targeting of insect epicuticular lipids by entomopathogenic fungi: hydrocarbon oxidation within the context of a host-pathogen interaction.
N. Pedrini, A. Ortiz Urquiza, C. Huarte Bonnet, S. Zhang, N.O. Keyhani.
2013. Frontiers in Microbiology 4: 24

Study of biochemical biomarkers in freshwater prawn Macrobrachium borellii (Crustacea: Palaemonidae) exposed to organophosphate fenitrothion.
S. Lavarias, C.F. García, R. Crespo, N. Pedrini, H. Heras.
2013. Ecotoxicology and Environmental Safety 96: 10-16

CYP52X1, representing a new cytochrome P450 subfamily, displays fatty acid hydroxylase activity and contributes to virulence and growth on insect cuticular substrates in the entomopathogenic fungus Beauveria bassiana.
S. Zhang, E. Widemann, G. Bernard, A. Lesot, F. Pinot, N. Pedrini, N.O. Keyhani.
2012. Journal of Biological Chemistry 287(16): 13477-13486

Insecticidal capacity of hydrocarbon-grown Beauveria bassiana to control Coleoptera on stored grain.
N. Pedrini, G. Dal Bello, S.B. Padín, M.P. Juárez.
2011. Agrociencia (Uruguay) 15(1): 64-69

Insecticidal effect of fenitrothion, diatomaceous earth and Beauveria bassiana against Coleopteran pests on stored grain.
G. Dal Bello, C. Fusé, M.P. Juárez, N. Pedrini, A. Imaz, S. Padín.
2011. Integrated Protection of Stored Products. IOBC/wprs Bulletin, 69: 175-180

Antioxidant response and oxidative stress levels in Macrobrachium borellii (Crustacea: Palaemonidae) exposed to the water-soluble fraction of petroleum.
S. Lavarías, H. Heras, N. Pedrini, H. Tournier, M. Ansaldo.
2011. Comparative Biochemistry and Physiology C 153(4): 415 – 421

Contribution of the horizontal transmission of the entomopathogenic fungus Beauveria bassiana to the overall performance of a fungal powder formulation against Triatoma infestans.
L. Forlani, N. Pedrini, M.P. Juárez.
2011. Research and Reports in Tropical Medicine 2: 135–140

Pyrethroid resistence in Chagas disease vectors: The case of Triatoma infestans cuticle.
M.P. Juárez, N. Pedrini, J.R. Girotti, S.J. Mijailovsky.
2010. Resistant Pest Management Newsletter, 19(2):59-61

Beauveria bassiana infection alters colony development and defensive secretions of the beetles Tribolium castaneum and Ulomoides dermestoides (Coleoptera: Tenebrionidae).
N. Pedrini, M.L. Villaverde, C.B. Fuse, G.M. Dal Bello, M.P. Juárez.
2010. Journal of Economical Entomology, 103(4): 1094-1099

Molecular characterization and expression analysis of a suite of cytochrome P450 enzymes implicated in insect hydrocarbon degradation in the entomopathogenic fungus Beauveria bassiana.
N. Pedrini, S. Zhang, M.P. Juárez, N.O. Keyhani.
2010. Microbiology (UK), 156: 2549 – 2557

Control of pyrethroid-resistant Chagas disease vectors with entomopathogenic fungi.
N. Pedrini, S.J. Mijailovsky, J.R. Girotti, R. Stariolo, R.M. Cardozo, A. Gentile, M.P. Juárez.
2009. PLoS Neglected Tropical Diseases 3(5): e434

Volatile secretions and epicuticular hydrocarbons of the beetle Ulomoides dermestoides.
M.L. Villaverde, J.R. Girotti, S.J. Mijailovsky, N. Pedrini, M.P. Juárez.
2009. Comparative Biochemistry and Physiology 154B:381-386

Volatile organic compounds released by the entomopathogenic fungus Beauveria bassiana.
R. Crespo, N. Pedrini, M.P. Juárez, G.M. Dal Bello.
2008. Microbiological Research, 163(2):148-151

Biochemistry of insect epicuticle degradation by entomopathogenic fungi.
N. Pedrini, R. Crespo, M.P. Juárez.
2007. Comparative Biochemistry and Physiology, 146C(1-2):124-137

Biocontrol of Acanthoscelides obtectus and Sitophilus orizae with diatomaceous earth and Beauveria bassiana on stored grains.
G.M. Dal Bello, S. Padín, M.P. Juárez, N. Pedrini, M. De Giusto.
2006. Biocontrol Science and Technology, 16(2): 215-220

Clues on the role of Beauveria bassiana catalases in alkane degradation events.
N. Pedrini, M.P. Juárez, R. Crespo, M.J. Tacconi de Alaniz.
2006. Mycologia, 98(4): 528-534

Increased mortality of Acanthoscelides obtectus by alkane-grown Beauveria bassiana.
R. Crespo, M.P. Juárez, G.M. Dal Bello, S.B. Padín, G. Calderón Fernández, N. Pedrini.
2002. BioControl, 47(6): 685-696

Efecto de la temperatura y humedad relativa sobre la mortalidad de Triatoma infestans susceptibles y resistentes a piretroides, expuestos a una cepa nativa de Beauveria bassiana de la región chaqueña, Salta-Argentina.
L.V. Baldiviezo, N. Pedrini, L.B. Nieva, R.M. Cardozo.
2022. En: Oliveira, A.M.C. (Ed), Interação parasito-hospedeiro. ISBN 978-65-5983-870-7. Atena, Ponta Grossa, Paraná, pp. 36-46
DOI: 10.22533/at.ed.7072226013

Entomopathogenic Fungi for the Control of Arthropod Pests.
I. da Costa Angelo, I., V.R.E.P. Bittencourt, E.K.K. Fernandes, P. Golo, N. Pedrini, J.L. Ramirez, eds.
2022. Lausanne: Frontiers Media SA.
doi.org/10.3389/978-2-88974-942-3

Toxic secondary metabolites and virulence factors expression by entomopathogenic fungi during insect infection and their potential impact as a tool for pest management.
M.C. Mannino, B. Davyt-Colo, N. Pedrini.
2021. En: Md. A. Khan, W. Ahmad (Eds.), Microbes for Sustainable lnsect Pest Management (Hydrolytic Enzyme & Secondary Metabolite – Volume 2) ISBN 978-3-030-67230-0. Springer-Nature, Basel, pp. 121-134
doi.org/10.1007/978-3-030-67231-7

Thermotolerance of conidia of entomopathogenic fungi.
F.R.S. Paixão, E.K.K. Fernandes, N. Pedrini.
2019. En: Md. A. Khan, W. Ahmad (Eds.), Microbes for Sustainable lnsect Pest Management (Sustainability in Plant and Crop Protection) ISBN 978-3-030-23044-9. Springer-Nature, Basel, pp. 189-200

Oxidative stress in entomopathogenic fungi and its potential role on mycoinsecticide enhancement.
C. Huarte-Bonnet, M.C. Mannino, N. Pedrini.
2019. En: Md. A. Khan, W. Ahmad (Eds.), Microbes for Sustainable lnsect Pest Management (Sustainability in Plant and Crop Protection) ISBN 978-3-030-23044-9. Springer-Nature, Basel, pp. 201-209

Análisis de la expresión de genes de hongos entomopatógenos mediante RT-PCR.
N. Pedrini, F. Consolo.
2013. En: C. Berón (Ed.), Manual de laboratorio: patología de insectos, 1ª ed., Universidad Nacional de Mar del Plata, Mar del Plata, pp.43-49

Entomopathogenic fungi and their host cuticle.
N. Pedrini, M.P. Juárez.
2008. En: J. Capinera (Ed.), Encyclopedia of Entomology (2nd. Edition). Springer-Verlag, Heidelberg, pp. 1333-1336

Mycoinsecticides against Chagas disease vectors: Biochemistry involved in insect host hydrocarbon degradation.
M.P. Juárez, N. Pedrini, R. Crespo.
2004. En: S. Mas-Comas (Ed.), Multidisciplinarity for Parasites, Vectors and Parasitic Diseases. Monduzzi Editore, Bologna, pp. 137-142

“Trampa para insectos hematófagos, método de control y método de detección de dichos insectos”
M. Patricia Juárez, Nicolás Pedrini, Juan R. Girotti, Sergio J. Mijailovsky, Alicia Lorenzo Figueiras.
Solicitud Nº P-080102268 (INPI 2008, en evaluación). Boletín Nº 568, pag. 5
Resolución AR068790A1 (Concedida 2015). Patentes concedidas 2015 enero - marzo, pag. 141

United States Patent Application Publication: “Bioinsecticide formulation comprising highly resistant Beauveria bassiana microsclerotia and method of preparation thereof”
Applicants: YPF Tecnología S.A., Ciudad Autónoma de Buenos Aires (AR); Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Ciudad Autónoma de Buenos Aires (AR); Universidad Nacional de La Plata (UNLP), La Plata (AR).
Inventors: Sebastián Alejandro Trejo; Sebastián Reinoso; Walter Alberto Vargas; Eliana Abrahamovich; Nicolás Pedrini; Juan Roberto Girotti; Marta Patricia Juárez.
Appl. No.: 16/811,381. Pub. No.: US 2020/0281215 A1. Pub. Date: Sep. 10, 2020

United States Patent Application Publication: “Sexual attraction pheromone of Tribolium castaneum and insect control device”
Applicants: YPF Tecnología S.A., Ciudad Autónoma de Buenos Aires (AR); Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Ciudad Autónoma de Buenos Aires (AR); Universidad Nacional de La Plata (UNLP), La Plata (AR).
Inventors: Sebastián Alejandro Trejo; Sebastián Reinoso; Walter Alberto Vargas; Eliana Abrahamovich; Nicolás Pedrini; Juan Roberto Girotti; Marta Patricia Juárez.
Appl. No.: 16/811,928. Pub. No.: US 2020/0281206 A1. Pub. Date: Sep. 10, 2020

Caracterización molecular de genes del hongo Beauveria bassiana involucrados en la captación y degradación de hidrocarburos de insecto.
Autor: Carla Huarte Bonnet
Director: Nicolás Pedrini
Facultad de Ciencias Exactas, UNLP, 2017Calificación: Aprobado con mención de honor.

“Chris J. Lomer Memorial Award, Society for Invertebrate Pathology”.
2008. Dr. Nicolás Pedrini.

“Preseleccionado para el premio Innovar” Categoría Investigación Aplicada. “Trampa para el control de vinchucas”
Juárez, M. P; Pedrini, N; Girotti, J. R; Mijailovsky, S.
2009. Ministerio de Ciencia, Tecnología e Innovación Productiva, República Argentina.

Premio Innovar Categoría Investigación Aplicada. “Trampa para el control de gorgojos en molinos harineros basada en un hongo entomopatógeno que sobreexpresa un factor de virulencia específico”
ID 14578. Pedrini, Nicolás; Girotti, Juan R.; Juárez, M. Patricia y Fuse, Cecilia.
2013. Ministerio de Ciencia, Tecnología e Innovación Productiva, República Argentina.




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